Onder andere met: Henry Fonda (Frank), Claudia Cardinale (Jill McBain), Jason Robards (Cheyenne), Charles Bronson (Harmonica), Gabriele Ferzetti (Morton (railroad baron)), Paolo Stoppa (Sam), Woody Strode (Stony (member of Frank`s gang)), Jack Elam (Snaky (member of Frank`s gang)), Keenan Wynn (Sheriff (auctioneer)), Frank Wolff (Brett McBain), Lionel Stander (Barman)