Onder andere met: Jason Mewes (Jay), Kevin Smith (Silent Bob), Ben Affleck (Holden McNeil/Himself), Jeff Anderson (Randal Graves), Brian O`Halloran (Dante Hicks (as Brian Christopher O`Halloran)), Shannon Elizabeth (Justice), Eliza Dushku (Sissy), Ali Larter (Chrissy), Jennifer Schwalbach Smith (Missy (as Jennifer Schwalbach)), Will Ferrell (Federal Wildlife Marshal Willenholly), Jason Lee (Brodie Bruce/Banky Edwards), Judd Nelson (Sheriff), George Carlin (Hitchhiker), Carrie Fisher (Nun), Seann William Scott (Brent),  Gus Van Sant (Himself), Chris Rock (Chaka Luther King), Jamie Kennedy (Chaka`s Production Assistant), Wes Craven (Himself), Shannen Doherty (Herself), Mark Hamill (Cocknocker), Joey Lauren Adams (Alyssa Jones), Alanis Morissette (That Woman (God)), Jason Biggs (Himself), Matt Damon (Himself/Will Hunting), James Van Der Beek (Himself)