Onder andere met: Christian Bale (John Connor), Sam Worthington (Marcus Wright), Moon Bloodgood (Blair Williams), Helena Bonham Carter (Dr. Serena Kogan), Anton Yelchin (Kyle Reese), Jadagrace (Star (as Jadagrace Berry)), Bryce Dallas Howard (Kate Connor), Common (Barnes), Jane Alexander (Virginia), Michael Ironside (General Ashdown), Ivan G'Vera (General Losenko), Chris Browning (Morrison), Dorian Nkono (David), Beth Bailey (Lisa), Victor J. Ho (Mark (as Victor Ho))