Onder andere met: Michael Jai White (Al Simmons / Spawn), John Leguizamo (Clown / Violator), Martin Sheen (Jason Wynn), Theresa Randle (Wanda Blake), Nicol Williamson (Cogliostro), D.B. Sweeney (Terry Fitzgerald), Melinda Clarke (Jessica Priest), Miko Hughes (Zack), Sydni Beaudoin (Cyan), Michael Papajohn (Glen, Zack's Dad), Frank Welker (The Devil Malebolgia (voice)), Robia LaMorte (XNN Reporter), Laura Stepp (Angela), Nick Danger (Himself)