Onder andere met: Jeff Goldblum (Seth Brundle), Geena Davis (Veronica Quaife), John Getz (Stathis Borans), Joy Boushel (Tawny), Leslie Carlson (Dr. Brent Cheevers), George Chuvalo (Marky), Michael Copeman (Second Man in Bar), David Cronenberg (Gynecologist), Carol Lazare (Nurse), Shawn Hewitt (Clerk)