Onder andere met: Jodie Foster (Clarice Starling), Anthony Hopkins (Dr. Hannibal Lecter), Scott Glenn (Jack Crawford), Anthony Heald (Dr. Frederick Chilton), Ted Levine (Jame 'Buffalo Bill' Gumb), Frankie Faison (Barney Matthews), Kasi Lemmons (Ardelia Mapp), Brooke Smith (Catherine Martin), Dan Butler (Roden), Charles Napier (Lt. Bill Boyle)