Onder andere met: Taylor Kitsch (John Carter), Lynn Collins (Dejah Thoris), Samantha Morton (Sola), Willem Dafoe (Tars Tarkas), Thomas Haden Church (Tal Hajus), Mark Strong (Matai Shang), Ciarán Hinds (Tardos Mors), Dominic West (Sab Than), James Purefoy (Kantos Kan), Bryan Cranston (Colonel Powell), Polly Walker (Sarkoja, a Thark), Daryl Sabara (Edgar Rice Burroughs), Nicholas Woodeson (Dalton), Don Stark (Dix, storekeeper in Arizona)