Onder andere met: Anson Mount (Cullen Bohannon), Colm Meaney (Thomas "Doc" Durant), Common (Elam Ferguson), Dominique McElligott (Lily Bell), Tom Noonan (Reverend Cole), Eddie Spears (Joseph Black Moon), Ben Esler (Sean McGinnes), Phil Burke (Mickey McGinnes), Christopher Heyerdahl (Thor Gundersen), Robin McLeavy (Eva Toole), Ted Levine (Captain Daniel Johnson), Wes Studi (Chief Many Horses), Kasha Kropinski ( Ruth, Reverend Cole's daughter), April Telek (Nell)