Onder andere met: Will Ferrell (Cam Brady), Zach Galifianakis (Marty Huggins), Jason Sudeikis (Mitch), Dylan McDermott (Tim Wattley), Katherine LaNasa (Rose Brady), Sarah Baker (Mitzi Huggins), John Lithgow (Glenn Motch), Dan Aykroyd (Wade Motch), Brian Cox (Raymond Huggins), Karen Maruyama (Mrs. Yao), Grant Goodman (Clay Huggins), Kya Haywood (Dylan Huggins), Randall D. Cunningham (Cam Jr. (as Randall Cunningham)), Madison Wolfe (Jessica Brady), Thomas Middleditch (Travis)