Onder andere met: Ian Richardson (Sherlock Holmes), Donald Churchill (Dr. John Watson), Denholm Elliott (Dr. Mortimer), Glynis Barber (Beryl Stapleton), Brian Blessed (Geoffrey Lyons), Eleanor Bron (Mrs. Barrymore), Edward Judd (Barrymore), Ronald Lacey (Inspector Lestrade), Martin Shaw (Sir Henry Baskerville), Connie Booth (Laura Lyons), Eric Richard (Cabbie), Michael Burrell (Shop Owner), Cindy O`Callaghan (Maid), Peter Rutherford (Selden), Francesca Gonshaw (Young Girl in Mire)